Analytical toxicology deals with the detection, identification and quantification of drugs and other foreign compounds (xenobiotics) and their metabolites in biological samples. It is important that the expert working in the field of analytical toxicology has sufficient clinical and forensic toxicology knowledge in diagnosis, laboratory management and evaluation of the results. Moreover, the expert must be able to communicate effectively with clinicians and judicial authorities during the interpretation of analysis results.
Analytical toxicology deals with the detection, identification and quantification of drugs and other foreign compounds (xenobiotics) and their metabolites in biological samples. It is important that the expert working in the field of analytical toxicology has sufficient clinical and forensic toxicology knowledge in diagnosis, laboratory management and evaluation of the results. Moreover, the expert must be able to communicate effectively with clinicians and judicial authorities during the interpretation of analysis results.
The Madame Lafarge case in 1840 was the first case in which chemical tests were used for the forensic identification of poison and intoxication. In the case of Madame Lafarge, who was tried for murdering her husband by poisoning him with arsenic, Orfila Mathieu, a chemistry teacher, had the body exhumed and found traces of arsenic in some organs when she examined it.
Over the last 25 years, there have been many advances in the reliability of analytical results in the detection, identification and measurement of drugs and other poisons in biological fluids. Some of these tests are applied for clinical purposes but require high analytical reliability because they may have medicolegal consequences. However, plasma drug level measurements (TDM) to support treatment, addictive substance analyzes in addiction treatment, and occupational chemical exposure tests for occupational health purposes have increased.
The main application areas of Analytical Toxicology are; Clinical Toxicology, Forensic Toxicology, Addictive Substance Screening, TDM, Occupational and Environmental Toxicology.
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Due to the nature of Analytical Toxicology research, it includes clinical toxicology, emergency toxicology, occupational toxicology analysis applications related to occupational health. In practice, communication between the toxicology laboratory and the clinician treating the patient must be very effective. Since the collection, transportation and storage of samples require different precautions, it is ideal to establish this communication before starting these procedures.
Today, toxicological screenings are normally performed using immunoassays. In addition, TDM (Therapeutic Drug Level Monitoring) tests are analyzed using immunoassay and chromatographic methods.
Our company offers solutions to the demands of medical laboratories regarding addictive substance screening analyzes and TDM analyses, with automated immunoassay systems and/or validated mass-spectrometry analysis kits whose quality and reliability have been proven in the scientific and laboratory world in this field.
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The Occupational Health and Safety Policy that we have adopted as Kaan Medikal is based on respect for people and the environment they live in. At Kaan Medikal, improving the health levels of its employees is seen as a requirement for work efficiency. In this direction; It provides a safe and healthy working environment by applying the Occupational Health and Safety System. As Kaan Medikal;
